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Adaptive changes result in activation of alternate signaling pathways and acquisition of resistance to aromatase inhibitors
Hormone therapy is an effective approach for the treatment of breast cancer. Although, the antiestrogen tamoxifen has had a major impact on the treatment of the disease, aromatase inhibitors, which reduce estrogen synthesis, have recently proved to be more effective. These agents are now used as fir...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131492/ https://ncbi.nlm.nih.gov/pubmed/21415222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2920 |
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