Nonhypoxic regulation and role of hypoxia-inducible factor 1 in aromatase inhibitor resistant breast cancer

INTRODUCTION: Although aromatase inhibitors (AIs; for example, letrozole) are highly effective in treating estrogen receptor positive (ER+) breast cancer, a significant percentage of patients either do not respond to AIs or become resistant to them. Previous studies suggest that acquired resistance...

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Detalhes bibliográficos
Main Authors: Kazi, Armina A, Gilani, Rabia A, Schech, Amanda J, Chumsri, Saranya, Sabnis, Gauri, Shah, Preeti, Goloubeva, Olga, Kronsberg, Shari, Brodie, Angela H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978891/
https://ncbi.nlm.nih.gov/pubmed/24472707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3609
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