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Adaptive changes result in activation of alternate signaling pathways and acquisition of resistance to aromatase inhibitors

Hormone therapy is an effective approach for the treatment of breast cancer. Although, the antiestrogen tamoxifen has had a major impact on the treatment of the disease, aromatase inhibitors, which reduce estrogen synthesis, have recently proved to be more effective. These agents are now used as fir...

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Detalhes bibliográficos
Main Authors: Brodie, Angela, Sabnis, Gauri
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131492/
https://ncbi.nlm.nih.gov/pubmed/21415222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2920
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