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Loss of T cell CD98hc specifically ablates T cell clonal expansion and protects from autoimmunity

CD98hc (CD98 heavy chain, 4F2 antigen, Slc3a2) was discovered as a lymphocyte activation antigen. Deletion of CD98hc in B cells leads to complete failure of B cell proliferation, plasma cell formation, and antibody secretion. Here we examined the role of T cell CD98 in cell-mediated immunity and aut...

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Bibliografski detalji
Glavni autori: Cantor, Joseph, Slepak, Marina, Ege, Nil, Chang, John T., Ginsberg, Mark H.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131465/
https://ncbi.nlm.nih.gov/pubmed/21670318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100002
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