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Loss of T cell CD98hc specifically ablates T cell clonal expansion and protects from autoimmunity
CD98hc (CD98 heavy chain, 4F2 antigen, Slc3a2) was discovered as a lymphocyte activation antigen. Deletion of CD98hc in B cells leads to complete failure of B cell proliferation, plasma cell formation, and antibody secretion. Here we examined the role of T cell CD98 in cell-mediated immunity and aut...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131465/ https://ncbi.nlm.nih.gov/pubmed/21670318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100002 |
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