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CD98hc facilitates B cell proliferation and adaptive humoral immunity
Proliferation of antigen-specific lymphocytes and resulting clonal expansion is essential for adaptive immunity. We report that B cell-specific deletion of CD98hc reduced antibody responses due to total suppression of B cell proliferation and subsequent plasma cell formation. Deletion of CD98hc didn...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672195/ https://ncbi.nlm.nih.gov/pubmed/19270713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1712 |
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