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FoxO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease

FoxO3 is a member of the forkhead box O (FoxO) transcription factor subfamily, which regulates the expression of target genes not only through DNA-binding as a transcription factor but also through protein-protein interaction. Although FoxO3 is a well-known transcription factor involved in diverse b...

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Bibliographische Detailangaben
Hauptverfasser: Hwang, Jae-woong, Rajendrasozhan, Saravanan, Yao, Hongwei, Chung, Sangwoon, Sundar, Isaac K., Huyck, Heidie L., Pryhuber, Gloria S., Kinnula, Vuokko L., Rahman, Irfan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131437/
https://ncbi.nlm.nih.gov/pubmed/21690325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001861
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