Peroxiredoxin 6 differentially regulates acute and chronic cigarette smoke–mediated lung inflammatory response and injury

Peroxiredoxin 6 (Prdx6) exerts its protective role through peroxidase activity against H(2)O(2) and phospholipid hydroperoxides. We hypothesized that targeted disruption of Prdx6 would lead to enhanced susceptibility to cigarette smoke (CS)-mediated lung inflammation and/or emphysema in mouse lung....

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Autores principales: Sundar, Isaac K., Chung, Sangwoon, Hwang, Jae-Woong, Arunachalam, Gnanapragasam, Cook, Suzanne, Yao, Hongwei, Mazur, Witold, Kinnula, Vuokko L., Fisher, Aron B., Rahman, Irfan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062974/
https://ncbi.nlm.nih.gov/pubmed/20939758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01902141003754128
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