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Generation of bivalent chromatin domains during cell fate decisions
BACKGROUND: In self-renewing, pluripotent cells, bivalent chromatin modification is thought to silence (H3K27me3) lineage control genes while 'poising' (H3K4me3) them for subsequent activation during differentiation, implying an important role for epigenetic modification in directing cell...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131236/ https://ncbi.nlm.nih.gov/pubmed/21645363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-4-9 |
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