Aldose Reductase and AGE–RAGE pathways: central roles in the pathogenesis of vascular dysfunction in aging rats

Aging is inevitably accompanied by gradual and irreversible innate endothelial dysfunction. In this study, we tested the hypothesis that accentuation of glucose metabolism via the aldose reductase (AR) pathway contributes to age-related vascular dysfunction. AR protein and activity levels were signi...

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Detaylı Bibliyografya
Asıl Yazarlar: Hallam, Kellie McCormick, Li, Qing, Ananthakrishnan, Radha, Kalea, Anastasia, Zou, Yu S., Vedantham, Srinivasan, Schmidt, Ann Marie, Yan, Shi Fang, Ramasamy, Ravichandran
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131144/
https://ncbi.nlm.nih.gov/pubmed/20670350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00606.x
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