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Gene Therapy in Mouse Models of Huntington Disease
Huntingtin, the protein that when mutated causes Huntington disease (HD), has many known interactors and participates in diverse cellular functions. Mutant Htt (mHtt) engages in a variety of aberrant interactions that lead to pathological gain of toxic functions as well as loss of normal functions....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131092/ https://ncbi.nlm.nih.gov/pubmed/21489966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1073858410386236 |
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