A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility

Susceptibility to testicular germ cell tumors (TGCT) has a significant heritable component, and genome-wide association studies (GWASs) have identified association with variants in several genes, including KITLG, SPRY4, BAK1, TERT, DMRT1 and ATF7IP. In our GWAS, we genotyped 349 TGCT cases and 919 c...

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Hlavní autoři: Kanetsky, Peter A., Mitra, Nandita, Vardhanabhuti, Saran, Vaughn, David J., Li, Mingyao, Ciosek, Stephanie L., Letrero, Richard, D'Andrea, Kurt, Vaddi, Madhavi, Doody, David R., Weaver, JoEllen, Chen, Chu, Starr, Jacqueline R., Håkonarson, Håkon, Rader, Daniel J., Godwin, Andrew K., Reilly, Muredach P., Schwartz, Stephen M., Nathanson, Katherine L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Association Studies Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131044/
https://ncbi.nlm.nih.gov/pubmed/21551455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr207
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