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A Wt1-Dmrt1 Transgene Restores DMRT1 to Sertoli Cells of Dmrt1(−/−) Testes: A Novel Model of DMRT1-Deficient Germ Cells1
DMRT1 is an evolutionarily conserved transcriptional factor expressed only in the postnatal testis, where it is produced in Sertoli cells and germ cells. While deletion of Dmrt1 in mice demonstrated it is required for postnatal testis development and fertility, much is still unknown about its tempor...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for the Study of Reproduction, Inc.
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589237/ https://ncbi.nlm.nih.gov/pubmed/23255335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.103135 |
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