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A Wt1-Dmrt1 Transgene Restores DMRT1 to Sertoli Cells of Dmrt1(−/−) Testes: A Novel Model of DMRT1-Deficient Germ Cells1

DMRT1 is an evolutionarily conserved transcriptional factor expressed only in the postnatal testis, where it is produced in Sertoli cells and germ cells. While deletion of Dmrt1 in mice demonstrated it is required for postnatal testis development and fertility, much is still unknown about its tempor...

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Detalhes bibliográficos
Main Authors: Agbor, Valentine A., Tao, Shixin, Lei, Ning, Heckert, Leslie L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589237/
https://ncbi.nlm.nih.gov/pubmed/23255335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.103135
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