Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors

Genome-wide association (GWA) studies of testicular germ cell tumor (TGCT) have identified 18 susceptibility loci, some containing genes encoding proteins important in male germ cell development. Deletions of one of these genes, DMRT1, lead to male-to-female sex reversal and are associated with deve...

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Detalhes bibliográficos
Main Authors: Koster, Roelof, Mitra, Nandita, D'Andrea, Kurt, Vardhanabhuti, Saran, Chung, Charles C., Wang, Zhaoming, Loren Erickson, R., Vaughn, David J., Litchfield, Kevin, Rahman, Nazneen, Greene, Mark H., McGlynn, Katherine A., Turnbull, Clare, Chanock, Stephen J., Nathanson, Katherine L., Kanetsky, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204765/
https://ncbi.nlm.nih.gov/pubmed/24943593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu305
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