Učitavanje...
Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus
BACKGROUND AND PURPOSE: Patients with diabetes mellitus require pharmacotherapy with numerous medications. However, the effect of diabetes on drug biotransformation is not well understood. Our goal was to investigate the effect of diabetes on liver cytochrome P450 3As, the most abundant phase I drug...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3130941/ https://ncbi.nlm.nih.gov/pubmed/21323901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01270.x |
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