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GROWTH FACTOR-DEPENDENT BRANCHING OF THE URETERIC BUD IS MODULATED BY SELECTIVE 6-O SULFATION OF HEPARAN SULFATE

Heparan sulfate proteoglycans (HSPGs) are found in the basement membrane and at the cell-surface where they modulate the binding and activity of a variety of growth factors and other molecules. Most of the functions of HSPGs are mediated by the variable sulfated glycosaminoglycan (GAG) chains attach...

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Detalhes bibliográficos
Main Authors: Shah, Mita M., Sakurai, Hiroyuki, Gallegos, Thomas F., Sweeney, Derina E., Bush, Kevin T., Esko, Jeffrey D., Nigam, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130836/
https://ncbi.nlm.nih.gov/pubmed/21600196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.05.004
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