PROTEIN KINASE A REGULATES GDNF/RET-DEPENDENT BUT NOT GDNF/RET-INDEPENDENT URETERIC BUD OUTGROWTH FROM THE WOLFFIAN DUCT

Embryonic kidney development begins with the outgrowth of the ureteric bud (UB) from the Wolffian duct (WD) into the adjacent metanephric mesenchyme (MM). Both a GDNF-dependent and GDNF-independent pathway have been identified. In vivo and in vitro, the GDNF-dependent pathway is inhibited by BMPs, o...

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Main Authors: Tee, James B., Choi, Yohan, Shah, Mita M., Dnyanmote, Ankur, Sweeney, Derina E., Gallegos, Tom F., Johkura, Kohei, Ito, Chiharu, Bush, Kevin T., Nigam, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981800/
https://ncbi.nlm.nih.gov/pubmed/20816800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.08.029
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