PROTEIN KINASE A REGULATES GDNF/RET-DEPENDENT BUT NOT GDNF/RET-INDEPENDENT URETERIC BUD OUTGROWTH FROM THE WOLFFIAN DUCT

Embryonic kidney development begins with the outgrowth of the ureteric bud (UB) from the Wolffian duct (WD) into the adjacent metanephric mesenchyme (MM). Both a GDNF-dependent and GDNF-independent pathway have been identified. In vivo and in vitro, the GDNF-dependent pathway is inhibited by BMPs, o...

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Auteurs principaux: Tee, James B., Choi, Yohan, Shah, Mita M., Dnyanmote, Ankur, Sweeney, Derina E., Gallegos, Tom F., Johkura, Kohei, Ito, Chiharu, Bush, Kevin T., Nigam, Sanjay K.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981800/
https://ncbi.nlm.nih.gov/pubmed/20816800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.08.029
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