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HS2ST MEDIATED KIDNEY MESENCHYME INDUCTION REGULATES EARLY URETERIC BUD BRANCHING

Heparan sulfate proteoglycans (HSPGs) are central modulators of developmental processes likely through their interaction with growth factors, such as GDNF, members of the FGF and TGFβ superfamilies, EGF receptor ligands and HGF. Absence of the biosynthetic enzyme, heparan sulfate 2-O-sulfotransferas...

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Detalhes bibliográficos
Main Authors: Shah, Mita M., Sakurai, Hiroyuki, Sweeney, Derina E., Gallegos, Thomas F., Bush, Kevin T., Esko, Jeffrey D., Nigam, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834281/
https://ncbi.nlm.nih.gov/pubmed/20059993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.12.033
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