Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction

We have determined the solution structure of the complex between an arginine-glycine-rich RGG peptide from the fragile X mental retardation protein (FMRP) and an in vitro-selected guanine-rich sc1 RNA. The bound RNA forms a novel G-quadruplex separated from the flanking duplex stem by a mixed juncti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Phan, Anh Tuân, Kuryavyi, Vitaly, Darnell, Jennifer C., Serganov, Alexander, Majumdar, Ananya, Ilin, Serge, Raslin, Tanya, Polonskaia, Anna, Chen, Cynthia, Clain, David, Darnell, Robert B., Patel, Dinshaw J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130835/
https://ncbi.nlm.nih.gov/pubmed/21642970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2064
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