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Identification of the yeast cytidine deaminase CDD1 as an orphan C→U RNA editase

Yeast co-expressing rat APOBEC-1 and a fragment of human apolipoprotein B (apoB) mRNA assembled functional editosomes and deaminated C6666 to U in a mooring sequence-dependent fashion. The occurrence of APOBEC-1-complementing proteins suggested a naturally occurring mRNA editing mechanism in yeast....

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Detalhes bibliográficos
Main Authors: Dance, Geoffrey S. C., Beemiller, Peter, Yang, Yan, Mater, David Van, Mian, I. Saira, Smith, Harold C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC31303/
https://ncbi.nlm.nih.gov/pubmed/11292850
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