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A Cytidine Deaminase Edits C to U in Transfer RNAs in Archaea

All canonical transfer RNAs (tRNAs) have a uridine at position 8, involved in maintaining tRNA tertiary structure. However, the hyperthermophilic archaeon Methanopyrus kandleri harbors 30 (out of 34) tRNA genes with cytidine at position 8. Here, we demonstrate C-to-U editing at this location in the...

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Detalhes bibliográficos
Main Authors: Randau, Lennart, Stanley, Bradford J., Kohlway, Andrew, Mechta, Sarah, Xiong, Yong, Söll, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857566/
https://ncbi.nlm.nih.gov/pubmed/19407206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1170123
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