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A Cytidine Deaminase Edits C to U in Transfer RNAs in Archaea

All canonical transfer RNAs (tRNAs) have a uridine at position 8, involved in maintaining tRNA tertiary structure. However, the hyperthermophilic archaeon Methanopyrus kandleri harbors 30 (out of 34) tRNA genes with cytidine at position 8. Here, we demonstrate C-to-U editing at this location in the...

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Détails bibliographiques
Auteurs principaux: Randau, Lennart, Stanley, Bradford J., Kohlway, Andrew, Mechta, Sarah, Xiong, Yong, Söll, Dieter
Format: Artigo
Langue:Inglês
Publié: 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857566/
https://ncbi.nlm.nih.gov/pubmed/19407206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1170123
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