Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

TALENs are important new tools for genome engineering. Fusions of transcription activator-like (TAL) effectors of plant pathogenic Xanthomonas spp. to the FokI nuclease, TALENs bind and cleave DNA in pairs. Binding specificity is determined by customizable arrays of polymorphic amino acid repeats in...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Cermak, Tomas, Doyle, Erin L., Christian, Michelle, Wang, Li, Zhang, Yong, Schmidt, Clarice, Baller, Joshua A., Somia, Nikunj V., Bogdanove, Adam J., Voytas, Daniel F.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130291/
https://ncbi.nlm.nih.gov/pubmed/21493687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr218
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki