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Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

TALENs are important new tools for genome engineering. Fusions of transcription activator-like (TAL) effectors of plant pathogenic Xanthomonas spp. to the FokI nuclease, TALENs bind and cleave DNA in pairs. Binding specificity is determined by customizable arrays of polymorphic amino acid repeats in...

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Detaylı Bibliyografya
Asıl Yazarlar: Cermak, Tomas, Doyle, Erin L., Christian, Michelle, Wang, Li, Zhang, Yong, Schmidt, Clarice, Baller, Joshua A., Somia, Nikunj V., Bogdanove, Adam J., Voytas, Daniel F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130291/
https://ncbi.nlm.nih.gov/pubmed/21493687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr218
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