HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer

Ovarian cancer frequently acquires resistance to platinum chemotherapy, representing a major challenge for improving patient survival. Recent work suggests resistant clones exist within a larger drug sensitive cell-population prior to chemotherapy, implying that resistance is selected for rather tha...

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Hlavní autoři: Stronach, Euan A, Alfraidi, Albandri, Rama, Nona, Datler, Christoph, Studd, Jamie, Agarwal, Roshan, Guney, Tankut G, Gourley, Charlie, Hennessy, Bryan T, Mills, Gordon B, Mai, Antonello, Brown, Robert, Dina, Roberto, Gabra, Hani
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130134/
https://ncbi.nlm.nih.gov/pubmed/21571862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4111
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