HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer

Ovarian cancer frequently acquires resistance to platinum chemotherapy, representing a major challenge for improving patient survival. Recent work suggests resistant clones exist within a larger drug sensitive cell-population prior to chemotherapy, implying that resistance is selected for rather tha...

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Detalhes bibliográficos
Main Authors: Stronach, Euan A, Alfraidi, Albandri, Rama, Nona, Datler, Christoph, Studd, Jamie, Agarwal, Roshan, Guney, Tankut G, Gourley, Charlie, Hennessy, Bryan T, Mills, Gordon B, Mai, Antonello, Brown, Robert, Dina, Roberto, Gabra, Hani
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130134/
https://ncbi.nlm.nih.gov/pubmed/21571862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4111
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