HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer

Ovarian cancer frequently acquires resistance to platinum chemotherapy, representing a major challenge for improving patient survival. Recent work suggests resistant clones exist within a larger drug sensitive cell-population prior to chemotherapy, implying that resistance is selected for rather tha...

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Hauptverfasser: Stronach, Euan A, Alfraidi, Albandri, Rama, Nona, Datler, Christoph, Studd, Jamie, Agarwal, Roshan, Guney, Tankut G, Gourley, Charlie, Hennessy, Bryan T, Mills, Gordon B, Mai, Antonello, Brown, Robert, Dina, Roberto, Gabra, Hani
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130134/
https://ncbi.nlm.nih.gov/pubmed/21571862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4111
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