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Modeling Platinum Sensitive and Resistant High-Grade Serous Ovarian Cancer: Development and Applications of Experimental Systems

High-grade serous ovarian cancer remains the most common sub-type of ovarian cancer and, characterized by high degrees of genomic instability and heterogeneity, is typified by a transition from early response to acquired resistance to platinum-based chemotherapy. Conventional models for the study of...

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Detalhes bibliográficos
Main Authors: Cunnea, Paula, Stronach, Euan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029026/
https://ncbi.nlm.nih.gov/pubmed/24860781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00081
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