Predictive Genes in Adjacent Normal Tissue Are Preferentially Altered by sCNV during Tumorigenesis in Liver Cancer and May Rate Limiting

BACKGROUND: In hepatocellular carcinoma (HCC) genes predictive of survival have been found in both adjacent normal (AN) and tumor (TU) tissues. The relationships between these two sets of predictive genes and the general process of tumorigenesis and disease progression remains unclear. METHODOLOGY/P...

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Autori principali: Lamb, John R., Zhang, Chunsheng, Xie, Tao, Wang, Kai, Zhang, Bin, Hao, Ke, Chudin, Eugene, Fraser, Hunter B., Millstein, Joshua, Ferguson, Mark, Suver, Christine, Ivanovska, Irena, Scott, Martin, Philippar, Ulrike, Bansal, Dimple, Zhang, Zhan, Burchard, Julja, Smith, Ryan, Greenawalt, Danielle, Cleary, Michele, Derry, Jonathan, Loboda, Andrey, Watters, James, Poon, Ronnie T. P., Fan, Sheung T., Yeung, Chun, Lee, Nikki P. Y., Guinney, Justin, Molony, Cliona, Emilsson, Valur, Buser-Doepner, Carolyn, Zhu, Jun, Friend, Stephen, Mao, Mao, Shaw, Peter M., Dai, Hongyue, Luk, John M., Schadt, Eric E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130029/
https://ncbi.nlm.nih.gov/pubmed/21750698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020090
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