Predictive Genes in Adjacent Normal Tissue Are Preferentially Altered by sCNV during Tumorigenesis in Liver Cancer and May Rate Limiting

BACKGROUND: In hepatocellular carcinoma (HCC) genes predictive of survival have been found in both adjacent normal (AN) and tumor (TU) tissues. The relationships between these two sets of predictive genes and the general process of tumorigenesis and disease progression remains unclear. METHODOLOGY/P...

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Detalhes bibliográficos
Main Authors: Lamb, John R., Zhang, Chunsheng, Xie, Tao, Wang, Kai, Zhang, Bin, Hao, Ke, Chudin, Eugene, Fraser, Hunter B., Millstein, Joshua, Ferguson, Mark, Suver, Christine, Ivanovska, Irena, Scott, Martin, Philippar, Ulrike, Bansal, Dimple, Zhang, Zhan, Burchard, Julja, Smith, Ryan, Greenawalt, Danielle, Cleary, Michele, Derry, Jonathan, Loboda, Andrey, Watters, James, Poon, Ronnie T. P., Fan, Sheung T., Yeung, Chun, Lee, Nikki P. Y., Guinney, Justin, Molony, Cliona, Emilsson, Valur, Buser-Doepner, Carolyn, Zhu, Jun, Friend, Stephen, Mao, Mao, Shaw, Peter M., Dai, Hongyue, Luk, John M., Schadt, Eric E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130029/
https://ncbi.nlm.nih.gov/pubmed/21750698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020090
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