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Magnitude of Stratification in Human Populations and Impacts on Genome Wide Association Studies

Genome-wide association studies (GWAS) may be biased by population stratification (PS). We conducted empirical quantification of the magnitude of PS among human populations and its impact on GWAS. Liver tissues were collected from 979, 59 and 49 Caucasian Americans (CA), African Americans (AA) and H...

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Detalhes bibliográficos
Main Authors: Hao, Ke, Chudin, Eugene, Greenawalt, Danielle, Schadt, Eric E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805717/
https://ncbi.nlm.nih.gov/pubmed/20084173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008695
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