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Magnitude of Stratification in Human Populations and Impacts on Genome Wide Association Studies

Genome-wide association studies (GWAS) may be biased by population stratification (PS). We conducted empirical quantification of the magnitude of PS among human populations and its impact on GWAS. Liver tissues were collected from 979, 59 and 49 Caucasian Americans (CA), African Americans (AA) and H...

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Autors principals: Hao, Ke, Chudin, Eugene, Greenawalt, Danielle, Schadt, Eric E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805717/
https://ncbi.nlm.nih.gov/pubmed/20084173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008695
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