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Deep mixed model for marginal epistasis detection and population stratification correction in genome-wide association studies

BACKGROUND: Genome-wide Association Studies (GWAS) have contributed to unraveling associations between genetic variants in the human genome and complex traits for more than a decade. While many works have been invented as follow-ups to detect interactions between SNPs, epistasis are still yet to be...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Wang, Haohan, Yue, Tianwei, Yang, Jingkang, Wu, Wei, Xing, Eric P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933893/
https://ncbi.nlm.nih.gov/pubmed/31881907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3300-9
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