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Magnitude of Stratification in Human Populations and Impacts on Genome Wide Association Studies

Genome-wide association studies (GWAS) may be biased by population stratification (PS). We conducted empirical quantification of the magnitude of PS among human populations and its impact on GWAS. Liver tissues were collected from 979, 59 and 49 Caucasian Americans (CA), African Americans (AA) and H...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hao, Ke, Chudin, Eugene, Greenawalt, Danielle, Schadt, Eric E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805717/
https://ncbi.nlm.nih.gov/pubmed/20084173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008695
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