DLK1-DIO3 Genomic Imprinted MicroRNA Cluster at 14q32.2 Defines a Stemlike Subtype of Hepatocellular Carcinoma Associated with Poor Survival

Hepatocellular carcinoma (HCC) is a heterogeneous and highly aggressive malignancy, for which there are no effective cures. Identification of a malignant stemlike subtype of HCC may offer patients with a dismal prognosis a potential targeted therapy using c-MET and Wnt pathway inhibitors. MicroRNAs...

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Bibliografski detalji
Glavni autori: Luk, John M., Burchard, Julja, Zhang, Chunsheng, Liu, Angela M., Wong, Kwong F., Shek, Felix H., Lee, Nikki P., Fan, Sheung Tat, Poon, Ronnie T., Ivanovska, Irena, Philippar, Ulrike, Cleary, Michele A., Buser, Carolyn A., Shaw, Peter M., Lee, Chuen-Neng, Tenen, Daniel G., Dai, Hongyue, Mao, Mao
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Molecular Bases of Disease
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162431/
https://ncbi.nlm.nih.gov/pubmed/21737452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.229831
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