A MicroRNA Cluster in the DLK1-DIO3 Imprinted Region on Chromosome 14q32.2 Is Dysregulated in Metastatic Hepatoblastomas

Hepatoblastoma (HB) is the most common malignant liver neoplasm in children. Despite progress in HB therapy, outcomes for patients with metastatic disease remain poor. Dysregulation of miRNA expression is one of the potential epigenetic mechanisms associated with pathogenesis of HB. However, miRNA p...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Oncol
Auteurs principaux: Honda, Shohei, Chatterjee, Aniruddha, Leichter, Anna L., Miyagi, Hisayuki, Minato, Masashi, Fujiyoshi, Sunao, Ara, Momoko, Kitagawa, Norihiko, Tanaka, Mio, Tanaka, Yukichi, Shinkai, Masato, Hatanaka, Kanako C., Taketomi, Akinobu, Eccles, Michael R.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Oncology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689214/
https://ncbi.nlm.nih.gov/pubmed/33282720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.513601
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