PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease

Parkinson’s disease affects 5 million people worldwide, but the molecular mechanisms underlying its pathogenesis are still unclear. Here, we report a genome-wide meta-analysis of gene sets (groups of genes that encode the same biological pathway or process) in 410 samples from patients with symptoma...

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Detalhes bibliográficos
Main Authors: Zheng, Bin, Liao, Zhixiang, Locascio, Joseph J., Lesniak, Kristen A., Roderick, Sarah S., Watt, Marla L., Eklund, Aron C., Zhang-James, Yanli, Kim, Peter D., Hauser, Michael A., Grünblatt, Edna, Moran, Linda B., Mandel, Silvia A., Riederer, Peter, Miller, Renee M., Federoff, Howard J., Wüllner, Ullrich, Papapetropoulos, Spyridon, Youdim, Moussa B., Cantuti-Castelvetri, Ippolita, Young, Anne B., Vance, Jeffery M., Davis, Richard L., Hedreen, John C., Adler, Charles H., Beach, Thomas G., Graeber, Manuel B., Middleton, Frank A., Rochet, Jean-Christophe, Scherzer, Clemens R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129986/
https://ncbi.nlm.nih.gov/pubmed/20926834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3001059
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