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Transcriptional Dysregulation in a Transgenic Model of Parkinson’s Disease

Alpha-synuclein has been implicated in Parkinson’s disease, yet the mechanism by which alpha-synuclein causes cell injury is not understood. Using a transgenic mouse model, we evaluated the effect of alpha-synuclein overexpression on gene expression in the substantia nigra. Nigral mRNA from wildtype...

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Detalhes bibliográficos
Main Authors: Yacoubian, Talene A., Cantuti-Castelvetri, Ippolita, Bouzou, Bérengère, Asteris, Georgios, McLean, Pamela J., Hyman, Bradley T., Standaert, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707844/
https://ncbi.nlm.nih.gov/pubmed/18191405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.11.008
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