Manufacturing DNA microarrays of high spot homogeneity and reduced background signal

Analyses on DNA microarrays depend considerably on spot quality and a low background signal of the glass support. By using betaine as an additive to a spotting solution made of saline sodium citrate, both the binding efficiency of spotted PCR products and the homogeneity of the DNA spots is improved...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Diehl, Frank, Grahlmann, Susanne, Beier, Markus, Hoheisel, Jörg D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	NAR Methods Online
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11266573/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.7.e38
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