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Manufacturing DNA microarrays of high spot homogeneity and reduced background signal

Analyses on DNA microarrays depend considerably on spot quality and a low background signal of the glass support. By using betaine as an additive to a spotting solution made of saline sodium citrate, both the binding efficiency of spotted PCR products and the homogeneity of the DNA spots is improved...

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Detalhes bibliográficos
Main Authors: Diehl, Frank, Grahlmann, Susanne, Beier, Markus, Hoheisel, Jörg D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC31299/
https://ncbi.nlm.nih.gov/pubmed/11266573
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