MicroRNA Regulation of Glycoprotein B5R in Oncolytic Vaccinia Virus Reduces Viral Pathogenicity Without Impairing Its Antitumor Efficacy

Vaccinia virus, once widely used for smallpox vaccine, has recently been engineered and used as an oncolytic virus for cancer virotherapy. Their replication has been restricted to tumors by disrupting viral genes and complementing them with products that are found specifically in tumor cells. Here,...

Full description

Saved in:
Bibliographic Details
Main Authors: Hikichi, Mina, Kidokoro, Minoru, Haraguchi, Takeshi, Iba, Hideo, Shida, Hisatoshi, Tahara, Hideaki, Nakamura, Takafumi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129806/
https://ncbi.nlm.nih.gov/pubmed/21386827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.36
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items