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Genetically stable and fully effective smallpox vaccine strain constructed from highly attenuated vaccinia LC16m8
A highly attenuated LC16m8 (m8) smallpox vaccine has been licensed in Japan because of its extremely low neurovirulence profile, which is comparable to that of replication incompetent strains of vaccinia virus. From 1973 to 1975, m8 was administrated to >100,000 infants where it induced levels of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC554788/ https://ncbi.nlm.nih.gov/pubmed/15753319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406671102 |
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