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Combined Cytolytic Effects of a Vaccinia Virus Encoding a Single Chain Trimer of MHC-I with a Tax-Epitope and Tax-Specific CTLs on HTLV-I-Infected Cells in a Rat Model
Adult T cell leukemia (ATL) is a malignant lymphoproliferative disease caused by human T cell leukemia virus type I (HTLV-I). To develop an effective therapy against the disease, we have examined the oncolytic ability of an attenuated vaccinia virus (VV), LC16m8Δ (m8Δ), and an HTLV-I Tax-specific cy...
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Główni autorzy: | , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
Hindawi Publishing Corporation
2014
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985193/ https://ncbi.nlm.nih.gov/pubmed/24791004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/902478 |
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