A Potential Role of Distinctively Delayed Blood Clearance of Recombinant Adeno-associated Virus Serotype 9 in Robust Cardiac Transduction

Recombinant adeno-associated virus serotype 9 (rAAV9) vectors show robust in vivo transduction by a systemic approach. It has been proposed that rAAV9 has enhanced ability to cross the vascular endothelial barriers. However, the scientific basis of systemic administration of rAAV9 and its transducti...

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Detalhes bibliográficos
Main Authors: Kotchey, Nicole M, Adachi, Kei, Zahid, Maliha, Inagaki, Katsuya, Charan, Rakshita, Parker, Robert S, Nakai, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129802/
https://ncbi.nlm.nih.gov/pubmed/21364543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.3
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