MicroRNA-sensitive Oncolytic Measles Viruses for Cancer-specific Vector Tropism

Oncolytic measles viruses (MV) derived from the live attenuated vaccine strain have been engineered for increased tumor-cell specificity, and are currently under investigation in clinical trials including a phase I study for glioblastoma multiforme (GBM). Recent preclinical studies have shown that t...

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Autors principals: Leber, Mathias F, Bossow, Sascha, Leonard, Vincent HJ, Zaoui, Karim, Grossardt, Christian, Frenzke, Marie, Miest, Tanner, Sawall, Stefanie, Cattaneo, Roberto, von Kalle, Christof, Ungerechts, Guy
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129790/
https://ncbi.nlm.nih.gov/pubmed/21468006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.55
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