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GP88 (PC-Cell Derived Growth Factor, progranulin) stimulates proliferation and confers letrozole resistance to aromatase overexpressing breast cancer cells
BACKGROUND: Aromatase inhibitors (AI) that inhibit breast cancer cell growth by blocking estrogen synthesis have become the treatment of choice for post-menopausal women with estrogen receptor positive (ER(+)) breast cancer. However, some patients display de novo or acquired resistance to AI. Intera...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129588/ https://ncbi.nlm.nih.gov/pubmed/21658239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-231 |
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