Rescue From Respiratory Dysfunction by Transduction of Full-length Dystrophin to Diaphragm via the Peritoneal Cavity in Utrophin/Dystrophin Double Knockout Mice

Duchenne muscular dystrophy (DMD) is an inherited severe muscle wasting disorder with, thus far, no effective therapy. DMD causes respiratory and cardiac failure as well as muscle wastage. Among the various symptoms, respiratory insufficiency is a major cause of death in DMD patients at about 20 yea...

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Autors principals: Ishizaki, Masatoshi, Maeda, Yasushi, Kawano, Ryoko, Suga, Tomohiro, Uchida, Yuji, Uchino, Katsuhisa, Yamashita, Satoshi, Kimura, En, Uchino, Makoto
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129567/
https://ncbi.nlm.nih.gov/pubmed/21467999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.58
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