Rescue From Respiratory Dysfunction by Transduction of Full-length Dystrophin to Diaphragm via the Peritoneal Cavity in Utrophin/Dystrophin Double Knockout Mice

Duchenne muscular dystrophy (DMD) is an inherited severe muscle wasting disorder with, thus far, no effective therapy. DMD causes respiratory and cardiac failure as well as muscle wastage. Among the various symptoms, respiratory insufficiency is a major cause of death in DMD patients at about 20 yea...

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Detalhes bibliográficos
Main Authors: Ishizaki, Masatoshi, Maeda, Yasushi, Kawano, Ryoko, Suga, Tomohiro, Uchida, Yuji, Uchino, Katsuhisa, Yamashita, Satoshi, Kimura, En, Uchino, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129567/
https://ncbi.nlm.nih.gov/pubmed/21467999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.58
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