Proteasome Inhibition Induces α-Synuclein SUMOylation and Aggregate Formation

Parkinson's disease (PD) and Dementia with Lewy bodies (DLB) are characterized pathologically by intraneuronal inclusions called Lewy bodies (LBs) and Lewy neurites. A major component of these inclusions is the protein α-synuclein, which is natively unfolded but forms oligomers and insoluble fi...

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Détails bibliographiques
Auteurs principaux: Kim, Yong Man, Jang, Won Hee, Quezado, Martha M., Oh, Yohan, Chung, Kwang Chul, Junn, Eunsung, Mouradian, M. Maral
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129438/
https://ncbi.nlm.nih.gov/pubmed/21641618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2011.04.015
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