Real-time visualization of heterotrimeric G protein Gq activation in living cells

BACKGROUND: Gq is a heterotrimeric G protein that plays an important role in numerous physiological processes. To delineate the molecular mechanisms and kinetics of signalling through this protein, its activation should be measurable in single living cells. Recently, fluorescence resonance energy tr...

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Detalhes bibliográficos
Main Authors: Adjobo-Hermans, Merel JW, Goedhart, Joachim, van Weeren, Laura, Nijmeijer, Saskia, Manders, Erik MM, Offermanns, Stefan, Gadella, Theodorus WJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129320/
https://ncbi.nlm.nih.gov/pubmed/21619590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-32
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