Real-time visualization of heterotrimeric G protein Gq activation in living cells

BACKGROUND: Gq is a heterotrimeric G protein that plays an important role in numerous physiological processes. To delineate the molecular mechanisms and kinetics of signalling through this protein, its activation should be measurable in single living cells. Recently, fluorescence resonance energy tr...

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Autores principales: Adjobo-Hermans, Merel JW, Goedhart, Joachim, van Weeren, Laura, Nijmeijer, Saskia, Manders, Erik MM, Offermanns, Stefan, Gadella, Theodorus WJ
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Methodology Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129320/
https://ncbi.nlm.nih.gov/pubmed/21619590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-32
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