Real-time visualization of heterotrimeric G protein Gq activation in living cells

BACKGROUND: Gq is a heterotrimeric G protein that plays an important role in numerous physiological processes. To delineate the molecular mechanisms and kinetics of signalling through this protein, its activation should be measurable in single living cells. Recently, fluorescence resonance energy tr...

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Bibliografske podrobnosti
Main Authors: Adjobo-Hermans, Merel JW, Goedhart, Joachim, van Weeren, Laura, Nijmeijer, Saskia, Manders, Erik MM, Offermanns, Stefan, Gadella, Theodorus WJ
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Methodology Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129320/
https://ncbi.nlm.nih.gov/pubmed/21619590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-32
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