Oligomerization and Binding of the Dnmt3a DNA Methyltransferase to Parallel DNA Molecules: HETEROCHROMATIC LOCALIZATION AND ROLE OF Dnmt3L

Structural studies showed that Dnmt3a has two interfaces for protein-protein interaction in the heterotetrameric Dnmt3a/3L C-terminal domain complex: the RD interface (mediating the Dnmt3a-3a contact) and the FF interface (mediating the Dnmt3a-3L contact). Here, we demonstrate that Dnmt3a-C forms di...

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Hauptverfasser: Jurkowska, Renata Z., Rajavelu, Arumugam, Anspach, Nils, Urbanke, Claus, Jankevicius, Gytis, Ragozin, Sergey, Nellen, Wolfgang, Jeltsch, Albert
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
DNA and Chromosomes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129201/
https://ncbi.nlm.nih.gov/pubmed/21566127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254987
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